Short Communications

  title={Short Communications},
  author={B F.M.},
  journal={Contact Dermatitis},
  • B. F.M.
  • Published 1 July 2000
  • Medicine
  • Contact Dermatitis
Contact allergy to topical corticosteroids is sufficiently common to justify their patch testing in standard series (1, 2). Frequently recommended are tixocortol pivalate as a screening test for class A (3) and budesonide for class B (4) corticosteroids. Tixocortol pivalate allergy was found in 0.9–4.4% of consecutive dermatitis patients (2, 5, 6), and budesonide allergy in 1.0–1.5% of such patients (6, 7). Several studies have shown equivalent patch test results whether testing with these 2… 



Patch testing with corticosteroid mixes in Europe

This study investigated whether a corticosteroid mix containing tixocortol pivalate, budesonide, and hydrocortisone‐17‐butyrate could detect contact allergy to corticosteroids. 2 corticosteroid

Patch testing with low concentrations of budesonide detects contact allergy

The patch test preparations internationally advocated are 0.1% in petrolatum (pet.) for budesonide and 1.0% pet.

Contact hypersensitivity to topical corticosteroids

The value of TP as a marker of corticosteroid hypersensitivity is reinforced by this study, but no satisfactory marker was found for the 9·2% of cases not detected by TP.

[Contact allergy to local steroids. Contact allergy to corticosteroids among consecutively tested patients with eczema].

In patients with longstanding eczematous skin disease, who do not improve or deteriorate during topical corticosteroid therapy, contact allergy to these drugs should be suspected and relevant patch tests should be performed to sort out concomitant reactions.

Contact hypersensitivity to corticosteroids in routine patch test patients. A multi-centre study of the Swiss Contact Dermatitis Research Group.

Corticosteroids should be included in routine patch testing, because contact sensitization to a corticosteroid is of considerable practical importance and tixocortol pivalate, budesonide and hydrocortisone butyrate may be suited, because there is no single cortiosteroid which is a marker for all four corticosterone groups.

Patch testing with budesonide in serial dilutions: the significance of dose, occlusion time and reading time *

Budesonide is advocated as a marker molecule for corticosteroid contact allergy and the dose‐response relationship for budesonide was investigated with regard to dose, occlusion time, and reading time, finding the “edge effect” was noted for several concentrations at early readings.

Contact hypersensitivity to tixocortol pivalate.

Probable active sensitization to tixocortol pivalate

This is, to the authors' knowledge, the 1st case of probable active sensitization to tixocortol pivalate to be reported, and although this can probably occur, it is likely to be rare.

Allergic contact dermatitis due to Euxyl® K 400 in an ultrasonic gel

Preservatives are widely used in medical preparations to achieve asepsis and Euxyl® K 400 is incorporated in leave-on cosmetics, shampoos, liquid soaps and other rinse-off products, and topical medicaments, and metalworking fluids may also contain it.

Stability of corticosteroid patch test preparations

The petrolatum preparations and the ethanolic solutions of budesonide and tixocortol pivalate were stable for at least the whole investigative period, irrespective of storage conditions, while Hc‐17‐B 1.0% in ethanol kept deep frozen was stable at least during the same period.