Short‐term outcomes after complete mesocolic excision compared with ‘conventional’ colonic cancer surgery

@article{Bertelsen2016ShorttermOA,
  title={Short‐term outcomes after complete mesocolic excision compared with ‘conventional’ colonic cancer surgery},
  author={C. A. Bertelsen and Anders Ulrich Neuenschwander and Jens Erik Jansen and Anders Kirkegaard-Klitbo and Jutaka Tenma and Michael Wilhelmsen and L A Rasmussen and Lars V. Jepsen and Bent Kristensen and Ismail G{\"o}genur},
  journal={British Journal of Surgery},
  year={2016},
  volume={103}
}
Complete mesocolic excision (CME) seems to be associated with improved oncological outcomes compared with ‘conventional’ surgery, but there is a potential for higher morbidity. 
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Oncological outcomes after complete mesocolic excision in right‐sided colon cancer: a population‐based study
TLDR
Evaluated the effect of CME surgery on colon cancer mortality after right‐sided hemicolectomy on a population level and proposes a new surgical technique for resection of colon cancer.
The risk of long‐term bowel dysfunction after resection for sigmoid adenocarcinoma: a cross‐sectional survey comparing complete mesocolic excision with conventional surgery
TLDR
To investigate whether complete mesocolic excision (CME) might carry a higher risk of bowel dysfunction and subsequent reduction in quality of life compared with conventional resection, a large number of patients were treated with CME.
Complete mesocolic excision versus conventional surgery for colon cancer: A systematic review and meta‐analysis
TLDR
Complete mesocolic excision lacks consistent data advocating operative superiority compared to conventional surgery for colon cancer, and population characteristics and perioperative, pathological and oncological outcomes are analyzed.
Oncological reasons for performing a complete mesocolic excision: a systematic review and meta‐analysis
While complete mesocolic excision (CME) has been shown to have an oncological benefit as compared to conventional colonic surgery for colon surgery, this benefit must be weighed up against the risk…
Safety, quality and effect of complete mesocolic excision vs non‐complete mesocolic excision in patients with colon cancer: a systemic review and meta‐analysis
  • C. Wang, Z. Gao, +7 authors Y. Ye
  • Medicine, Biology
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • 2017
TLDR
A meta‐analysis was performed to compare the safety, quality and effect of CME with non‐complete mesocolic excision (NCME) in patients with colon cancer.
Recurrence after complete mesocolic excision for right‐sided colon cancer: post hoc sensitivity analyses—early recurrence, surgery by specialist and dissection in the mesocolic plane
TLDR
The absolute risk reduction of recurrence after complete mesocolic excision for right-sided colon cancer in the previous study was not biased by potentially undiagnosed disseminated disease at the time of surgery, non-specialist surgery, and was not solely caused by dissection in the Mesocolic plane.
Prognosis of patients with colonic carcinoma before, during and after implementation of complete mesocolic excision
The implementation of complete mesocolic excision (CME) for colonic cancer was accompanied by other important changes, including more patients with early diagnosis by screening and the introduction…
The effect of a multidisciplinary regional educational programme on the quality of colon cancer resection
  • G. Sheehan-Dare, K. Marks, +4 authors N. West
  • Medicine
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • 2018
TLDR
This data indicates that mesocolic plane surgery with central vascular ligation produces an oncologically superior specimen following colon cancer resection and appears to be related to optimal outcomes.
The safety of complete mesocolic excision once again confirmed
  • C. Bertelsen, A. Neuenschwander
  • Medicine
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • 2018
TLDR
Further evidence supporting complete mesocolic excision (CME) as a safe approach in colon cancer surgery is published and there is no increased risk of 30-day mortality or reoperation after right-sided CME in a nested case-control study.
Robotic complete mesocolic excision and central vascular ligation for right‐sided colon cancer: short‐term outcomes from a case series
TLDR
The safety profile of CME and CVL in patients undergoing robotic surgery for right‐sided colon cancer during the introduction of this technique across two institutions is reported.
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TLDR
The aim of this study was to evaluate the evidence regarding oncological outcomes, morbidity and mortality after such techniques for colon cancer.
Standardized surgery for colonic cancer: complete mesocolic excision and central ligation – technical notes and outcome
TLDR
This technique is focused on an intact package of the tumour and its main lymphatic drainage and this technique is nowadays accepted worldwide for optimal rectal cancer surgery.
Can the quality of colonic surgery be improved by standardization of surgical technique with complete mesocolic excision?
Aim  we analysed the influence of standardization of colon cancer surgery with complete mesocolic excision (CME) on the quality of surgery measured by the pathological end‐points of number of…
Morphometric analysis and lymph node yield in laparoscopic complete mesocolic excision performed by supervised trainees
Complete mesocolic excision with central vascular ligation (CME) produces an optimal colonic cancer specimen. The ability of expert laparoscopic surgeons to produce equivalent specimens is unknown.
Outcome after Introduction of Complete Mesocolic Excision for Colon Cancer Is Similar for Open and Laparoscopic Surgical Treatments
TLDR
There was no survival difference between open and laparoscopic CME colonic resections, and the present OS improved from a previous OS from 2000, while the surgical approach was not a significant predictor for any of the survival parameters.
Population-based study of laparoscopic colorectal cancer surgery 2006–2008
TLDR
This study aimed to examine the introduction of laparoscopic surgery in the English National Health Service and found no change in the number of patients with colorectal cancer or in the quality of their care.
Complete mesocolic excision with D3 lymph node dissection in laparoscopic colectomy for stages II and III colon cancer: long-term oncologic outcomes in 168 patients
TLDR
Standardization of laparoscopic CME and D3 lymphadenectomy is expedient and provides excellent oncologic outcomes for stage II and stage III colon cancer.
Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon.
TLDR
Surgeons in Erlangen routinely practicing CME and CVL surgery remove more mesocolon and are more likely to resect in the mesocolic plane when compared with standard excisions, which may partially explain the high 5-year survival rates reported inErlangen.
Modified complete mesocolic excision with central vascular ligation for the treatment of right-sided colon cancer: long-term outcomes and prognostic factors.
TLDR
The mCME technique, on the basis of the same principle as CME, but with a more tailored approach, has successfully established the long-term oncologic outcomes and risk of postoperative morbidity that were comparable with those seen with the original CME procedure.
Laparoscopic-Assisted Versus Open Complete Mesocolic Excision and Central Vascular Ligation for Right-Sided Colon Cancer
TLDR
Although LCME for right-sided colon cancer was associated with better 5-year overall survival, compared with an open approach, the long-term oncologic outcomes between the groups were comparable and the feasibility and safety of LCME was demonstrated.
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