Shock wave application to rat skin induces degeneration and reinnervation of sensory nerve fibres.

@article{Ohtori2001ShockWA,
  title={Shock wave application to rat skin induces degeneration and reinnervation of sensory nerve fibres.},
  author={Seiji Ohtori and Gen Inoue and Chikato Mannoji and Takashi Saisu and Ken Takahashi and Shigeru Mitsuhashi and Yuichi Wada and Munehisa Yamagata and Hideshige Moriya},
  journal={Neuroscience letters},
  year={2001},
  volume={315 1-2},
  pages={57-60}
}
There have been several reports on the use of extracorporeal shock waves in the treatment of pseudarthrosis, calcifying tendinitis, and tendinopathies of the elbow. However, the pathomechanism of pain relief has not been clarified. To investigate the analgesic properties of shock wave application, we analyzed whether it produces morphologic changes in cutaneous nerve fibres. In normal rat skin, the epidermis is heavily innervated by nerve fibres immunoreactive for protein gene product (PGP) 9.5… CONTINUE READING