Shivering and nonshivering thermogenesis in exercised cold-deacclimated rats

  title={Shivering and nonshivering thermogenesis in exercised cold-deacclimated rats},
  author={Kiyoshi Moriya and J Arnold and Jacques Leblanc},
  journal={European Journal of Applied Physiology and Occupational Physiology},
SummaryNorepinephrine (NE)-induced increase in oxygen consumption ( $$\dot V_{{\text{O}}_{\text{2}} } $$ ) and colonic temperature (Tc) was greater in cold-acclimated rats housed at 4° C for 4 weeks (CA) than warm-acclimated controls housed at 24° C for 4 weeks (WA). On the other hand, shivering activity measured at 4° C was less in CA than in WA, while propranolol administration eliminated the difference between these two groups by enhancing shivering in CA. Wet weight and protein content of… 
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Circadian rhythmicity of body temperature and metabolism
The circadian system modulates metabolic heat production to generate the body temperature rhythm, which challenges homeothermy but does not abolish it, meaning that circadian rhythmicity and metabolism are intertwined in the cell.


Effects of exercise and intermittent cold exposure on shivering and nonshivering thermogenesis in rats.
It is suggested that exercise training in rats housed at 24 degrees C suppresses NE-dependent NST whereas another nonshivering thermogenic mechanism (NE-independent) may compensate this suppression.
Potentiated muscular thermogenesis in cold-acclimated muscovy duckling.
Results indicated an increased thermogenic efficiency of muscular activity in CA ducklings, devoid of brown adipose tissue, which is more resistant to cold and had higher peak metabolic rate in extreme cold.
Similarities between cold- and diet-induced thermogenesis in the rat
Experimental groups showed an increased capacity to respond to the thermogenic effects of norepinephrine and greather deposits of interscapular brown adipose tissue (IBAT) compared with WAS controls.
Effect of exercise training on the disappearance of cold adaptability in rats
  • K. Moriya
  • Biology, Psychology
    European Journal of Applied Physiology and Occupational Physiology
  • 2006
Triiodothyronine (T3), the physiologically most active thyroid hormone, was at a higher plasma level in cold- Adapted rats than in de-adapted animals with or without exercise loads, and although the resting level of T3 in running-trained rats was not higher than that in sedentary rats, some fluctuations of T2 level were observed during running.
Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline.
Flow to heart and to muscles involved in respiratory movements was two to five times greater during calorigenesis and flow to most other tissues and organs increased or decreased by less than 40%.
Noradrenaline-induced calorigenesis in warm- and cold-acclimated rats: relations between concentration of noradrenaline in arterial plasma, blood flow to differently located masses of brown adipose tissue, and calorigenic response.
It is concluded that the differently located bodies of BAT in rats may have significant differences in composition and structure and that they may undergo differential development during cold acclimation.
Exercise during intermittent cold exposure prevents acclimation to cold rats.
Treadmill running during daily, 2 h exposure at ‐5 degrees C appears to prevent the cold acclimation responses that occur in sedentary rats receiving similar cold exposure.
Thermogenesis in human brown adipose tissue and skeletal muscle induced by sympathomimetic stimulation.
  • A. Astrup
  • Biology, Medicine
    Acta endocrinologica. Supplementum
  • 1986
The aim of the present work was to elucidate the importance of brown adipose tissue (BAT) and skeletal muscle for ephedrine-induced thermogenesis, and to examine the effect of chronic ephedrine
Glucagon stimulation of brown adipose tissue growth and thermogenesis.
The ability of administered glucagon to produce alterations in brown adipose tissue similar to changes produced by accepted stimuli of brown fat activity: cold, norepinephrine, and overfeeding is investigated.
Do corticosteroids control heat production in hibernators?
In hedgehogs two different control mechanisms of non-shivering thermogenesis (NST) exist: during arousal from hibernation catecholamines control heat production in the interscapular brown adipose tissue and in a non-hibernating state, cold-induced NST is controlled by a desoxycorticosterone-like acting compound.