Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh protein

@article{Beloin2003ShigellaF2,
  title={Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh protein},
  author={Christophe Beloin and Padraig Deighan and Michael Doyle and Charles J Dorman},
  journal={Molecular Genetics and Genomics},
  year={2003},
  volume={270},
  pages={66-77}
}
Shigella flexneri 2a is known to express the H-NS nucleoid-structuring protein and the paralogous protein StpA. Using bioinformatic analysis we have now discovered a third member of the H-NS protein family, Sfh (S higella f lexneri H-NS-like protein), in strain 2457T. This protein is encoded by the sfh gene, which is located on a high-molecular-mass plasmid that is closely related to the self-transmissible plasmid R27. When expressed in Escherichia coli, the Sfh protein can complement an hns… CONTINUE READING

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