Shiga toxins expressed by human pathogenic bacteria induce immune responses in host cells


Shiga toxins are a family of genetically and structurally related toxins that are the primary virulence factors produced by the bacterial pathogens Shigella dysenteriae serotype 1 and certain Escherichia coli strains. The toxins are multifunctional proteins inducing protein biosynthesis inhibition, ribotoxic and ER stress responses, apoptosis, autophagy… (More)
DOI: 10.1007/s12275-013-3429-6


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