Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement.

@article{Newton2009ShigaTE,
  title={Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement.},
  author={Hayley J. Newton and Joan Sloan and Dieter M Bulach and Torsten Seemann and Cody C. Allison and Marija Tauschek and Roy M Robins-Browne and James C. Paton and Thomas S. Whittam and Adrienne W. Paton and Elizabeth L. Hartland},
  journal={Emerging infectious diseases},
  year={2009},
  volume={15 3},
  pages={
          372-80
        }
}
Most Shiga toxin-producing Escherichia coli (STEC) infections that are associated with severe sequelae such as hemolytic uremic syndrome (HUS) are caused by attaching and effacing pathogens that carry the locus of enterocyte effacement (LEE). However, a proportion of STEC isolates that do not carry LEE have been associated with HUS. To clarify the emergence of LEE-negative STEC, we compared the genetic composition of the virulence plasmids pO113 and pO157 from LEE-negative and LEE-positive STEC… Expand
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