Shifting of activation center in the brain during muscle fatigue: an explanation of minimal central fatigue?

@article{Liu2007ShiftingOA,
  title={Shifting of activation center in the brain during muscle fatigue: an explanation of minimal central fatigue?},
  author={Jing Zhang Liu and Beth E. Lewandowski and Chris Karakasis and Bing Yao and Vlodek Siemionow and Vinod Sahgal and Guang H. Yue},
  journal={NeuroImage},
  year={2007},
  volume={35 1},
  pages={299-307}
}
Accumulating evidence suggests that the overall level of cortical activation controlling a voluntary motor task that leads to significant muscle fatigue does not decrease as much as the activation level of the motoneuron pool projecting to the muscle. One possible explanation for this "muscle fatigue>cortical fatigue" phenomenon is that the brain is an organ with built-in redundancies: it has multiple motor centers and parallel pathways, and the center of activation may shift from one location… CONTINUE READING