Shifting constraints on tRNA genes during mitochondrial DNA evolution in animals.

@article{Thomas1989ShiftingCO,
  title={Shifting constraints on tRNA genes during mitochondrial DNA evolution in animals.},
  author={W. Thomas and Jan Maa and A. C. Wilson},
  journal={The New biologist},
  year={1989},
  volume={1 1},
  pages={93-100}
}
During the evolution of echinoderm mitochondrial (mt) DNA, a transfer RNA gene lost its tRNA function and became part of a protein-coding gene. To examine the evolutionary consequences of this event, we sequenced 961 bp of mtDNA in five sea urchin species. This enabled us to build a tree relating the mtDNAs and use it for analyzing the pattern and process of evolutionary substitutions in the former leucine tRNA gene, which now is a 5' extension of the gene for NADH dehydrogenase subunit 5 (ND5… CONTINUE READING

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