Sheep models of intrauterine growth restriction: fetal adaptations and consequences.

@article{Morrison2008SheepMO,
  title={Sheep models of intrauterine growth restriction: fetal adaptations and consequences.},
  author={Janna L Morrison},
  journal={Clinical and experimental pharmacology & physiology},
  year={2008},
  volume={35 7},
  pages={730-43}
}
1. Intrauterine growth restriction (IUGR) has been associated with poor perinatal health outcomes. Animal models have been used to investigate why IUGR is associated with a poor prognosis. The sheep has been used extensively as an experimental model for IUGR with poor placental substrate supply to the fetus induced using a range of methods, including the surgical ablation of the majority of endometrial caruncles prior to conception, experimental induction of maternal hyperthermia, ligation of… CONTINUE READING
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