Sheep, pig, and human platelet-material interactions with model cardiovascular biomaterials.

@article{Goodman1999SheepPA,
  title={Sheep, pig, and human platelet-material interactions with model cardiovascular biomaterials.},
  author={Steven L. Goodman},
  journal={Journal of biomedical materials research},
  year={1999},
  volume={45 3},
  pages={
          240-50
        }
}
The relationship between cardiovascular device performance in animals and humans is not straightforward. As the principal formed element in a thrombus, platelets play a major role in determining the hemocompatibility of mechanical heart valves and other high-shear-rate cardiovascular devices. Since larger animals are required to test many such devices, sheep and porcine platelet responses were compared to humans. Adhesion, spreading, and the formation of thrombilike structures were examined in… CONTINUE READING
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Imaging of explanted mechanical heart valves

  • SL Goodman, H Harasaki, EK Wika, AM Brendzel
  • Microscopy and Micro - analysis ’ 98
  • 1998

Imaging of explanted mechanical heart valves. In: Microscopy and Microanalysis ’98

  • SL Goodman, H Harasaki, EK Wika, AM. Brendzel
  • 1998
2 Excerpts

The development and evaluation of a swine model to assess the preclinical safety of intra - cardiac prothetic devices

  • JF Grehan, CT Salerno, RW Bianco
  • Workshop on Prosthetic Heart valves : Future…
  • 1998

The development and evaluation of a swine model to assess the preclinical safety of intra-cardiac prothetic devices. In: Workshop on Prosthetic Heart valves: Future

  • JF Grehan, CT Salerno, RW. Bianco
  • 1998

The pig as an in vivo model for the evaluation of the thrombogenicity of mechanical heart

  • OD Henneman, GL Van Rijk-Zwikker, EF Bruggemans, FR Rosendaal, BJ Delemarre, HA. Huysmans
  • valves. In: Workshop on Prosthetic Heart valves…
  • 1998

The pig as an in vivo model for the evaluation of the thrombogenicity of mechanical heart valves

  • OD Henneman, GL VanRijk-Zwikker, EF Bruggemans, FR Rosendaal, BJ Delemarre, HA Huysmans
  • Workshop on Prosthetic Heart valves : Future…
  • 1998

Threedimensional SEM of explanted pyrolytic carbon mechanical heart valves

  • SL Goodman, KE Wika, AM Brendzel, H. Harasaki
  • Trans Soc Biomat
  • 1998
3 Excerpts

Microscopical imaging of pyrolytic carbon and difficult to image biomaterials (a tutorial)

  • SL Goodman
  • Cells Mater
  • 1997
1 Excerpt

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