Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies.


OBJECTIVE To investigate whether syncytiotrophoblast microvilli (STBM) are shed into the maternal circulation in increased amounts in pre-eclamptic pregnancies as a possible cause of maternal vascular endothelial dysfunction. DESIGN A time-resolved fluoroimmunoassay was developed to measure STBM levels in peripheral and uterine venous plasma from normal… (More)


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