Shed membrane fragment-associated markers for endometrial and ovarian cancers.

@article{Taylor2002ShedMF,
  title={Shed membrane fragment-associated markers for endometrial and ovarian cancers.},
  author={Douglas D. Taylor and Karen S. Lyons and Ciçek Gerçel-Taylor},
  journal={Gynecologic oncology},
  year={2002},
  volume={84 3},
  pages={443-8}
}
OBJECTIVE The objective of this study was to assess circulating tumor-derived membrane fragments (MFs) and specific proteins associated with them as diagnostic and prognostic markers for ovarian and endometrial cancers. METHODS The level of shed tumor-derived plasma MFs was analyzed chromatographically on high exclusion limit agarose-based gels, using sera from non-cancer-bearing female controls (n = 50), women with ovarian disease (benign, n = 43, and stages III and IV ovarian cancer, n = 62… CONTINUE READING