Shear stress-induced collagen XII expression is associated with atherogenesis.

@article{Jin2003ShearSC,
  title={Shear stress-induced collagen XII expression is associated with atherogenesis.},
  author={Xin Jin and Satoshi Iwasa and Kyoko Okada and Akishi Ooi and Kazuhiro Mitsui and Masako Mitsumata},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={308 1},
  pages={152-8}
}
Fluid shear stress has been shown to modulate various endothelial functions. We selected a shear stress-specific clone, identified as collagen XII, from a bovine aortic endothelial cell (BAEC) cDNA library. We confirmed that shear stress induces collagen XII expression at both the mRNA and protein levels in cultured BAECs and human umbilical vein ECs… CONTINUE READING