Shear stress, the endothelium and the balance between flow-induced contraction and dilation in animals and man.

  • John A. Bevan
  • Published 1997 in
    International journal of microcirculation…
Dilation is the most commonly observed diameter change in blood vessels when intraluminal flow increases. However, at very high and low levels of vascular tone the response is constriction. This complex response seems designed to ensure that time-averaged vascular tone levels are restricted to an intermediate range. Flow dilation is initiated predominantly… CONTINUE READING