Shear flow increases S-nitrosylation of proteins in endothelial cells.

Abstract

AIMS Endothelial cells (ECs) constantly exposed to shear flow increase nitric oxide production via the activation of endothelial nitric oxide synthase. Nitric oxide-mediated S-nitrosylation has recently been identified as an important post-translational modification that may alter signalling and/or protein function. S-nitrosylation of endothelial proteins… (More)
DOI: 10.1093/cvr/cvp154

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