Shear acoustic wave biosensor for detecting DNA intrinsic viscosity and conformation: a study with QCM-D.

Abstract

Direct biosensors are devices operating by monitoring the amount of surface-bound analyte. In this work a new approach is presented where a label-free acoustic biosensor, based on a QCM-D device, and solution viscosity theory, are used to study DNA intrinsic viscosity. The latter is quantitatively related to the DNA conformation and specifically the… (More)
DOI: 10.1016/j.bios.2008.07.006

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