Sharpened Cochlear Tuning in a Mouse with a Genetically Modified Tectorial Membrane

@inproceedings{Russell2007SharpenedCT,
  title={Sharpened Cochlear Tuning in a Mouse with a Genetically Modified Tectorial Membrane},
  author={Ian John Russell and P. Kevin Legan and Victoria A. Lukashkina and Andrei N Lukashkin and Richard J Goodyear and Guy. P Richardson},
  booktitle={Nature Neuroscience},
  year={2007}
}
Frequency tuning in the cochlea is determined by the passive mechanical properties of the basilar membrane and active feedback from the outer hair cells, sensory-effector cells that detect and amplify sound-induced basilar membrane motions. The sensory hair bundles of the outer hair cells are imbedded in the tectorial membrane, a sheet of extracellular matrix that overlies the cochlea's sensory epithelium. The tectorial membrane contains radially organized collagen fibrils that are imbedded in… CONTINUE READING
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