Sharing of virulent Escherichia coli clones among household members of a woman with acute cystitis.

@article{Johnson2006SharingOV,
  title={Sharing of virulent Escherichia coli clones among household members of a woman with acute cystitis.},
  author={James R. Johnson and Connie 7 Clabots},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2006},
  volume={43 10},
  pages={e101-8}
}
BACKGROUND Within-household transmission of extraintestinal pathogenic Escherichia coli (ExPEC) may contribute to the pathogenesis of urinary tract infection (UTI), but this is poorly understood. METHODS A woman with acute UTI, 4 human household members who cohabited with her, and the family's pet dog underwent prospective longitudinal surveillance for colonizing E. coli for 7-9 weeks after the woman's UTI episode. Unique clones were resolved by random amplified polymorphic DNA and pulsed… CONTINUE READING