Shared motifs of the capsid proteins of hepadnaviruses and retroviruses suggest a common evolutionary origin.

@article{Zlotnick1998SharedMO,
  title={Shared motifs of the capsid proteins of hepadnaviruses and retroviruses suggest a common evolutionary origin.},
  author={Adam Zlotnick and Stephen J. Stahl and Paul T Wingfield and James F Conway and Naiqian Cheng and Alasdair C. Steven},
  journal={FEBS letters},
  year={1998},
  volume={431 3},
  pages={301-4}
}
The structure of the dimeric C-terminal domain of the HIV-1 capsid protein (CA), recently determined by X-ray crystallography (Gamble et al. (1997)), has a notable resemblance to the structure of the hepatitis B virus (HBV) capsid protein (Cp) dimer, previously determined by cryo-electron microscopy (Conway et al. (1997), Böttcher et al. (1997)). In both proteins, dimerization is effected by formation of a four-helix bundle, whereby each subunit contributes a helix-loop-helix and most of the… CONTINUE READING

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