Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.

@article{Chan2014SharedMP,
  title={Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.},
  author={Kei Hang K Chan and Yen-Tsung Huang and Qingying Meng and Chunyuan Wu and Alex P. Reiner and Eric M. Sobel and Lesley F Tinker and Aldons J. Lusis and Xia Yang and Simin Liu},
  journal={Circulation. Cardiovascular genetics},
  year={2014},
  volume={7 6},
  pages={911-9}
}
BACKGROUND Although cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D) share many common risk factors, potential molecular mechanisms that may also be shared for these 2 disorders remain unknown. METHODS AND RESULTS Using an integrative pathway and network analysis, we performed genome-wide association studies in 8155 blacks, 3494 Hispanic American, and 3697 Caucasian American women who participated in the national Women's Health Initiative single-nucleotide polymorphism (SNP… CONTINUE READING
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