Shared genetic factors in migraine and depression: evidence from a genetic isolate.

  title={Shared genetic factors in migraine and depression: evidence from a genetic isolate.},
  author={Anine H. Stam and Bert B A de Vries and Anne-Sophie Janssens and Kaate R J Vanmolkot and Yurii S. Aulchenko and Peter Henneman and Ben A. Oostra and Rune R. Frants and Arn M J M van den Maagdenberg and Michel D. Ferrari and Cornelia M van Duijn and Gisela M. Terwindt},
  volume={74 4},
OBJECTIVE To investigate the co-occurrence of migraine and depression and assess whether shared genetic factors may underlie both diseases. METHODS Subjects were 2,652 participants of the Erasmus Rucphen Family genetic isolate study. Migraine was diagnosed using a validated 3-stage screening method that included a telephone interview. Symptoms of depression were assessed using the Center for Epidemiologic Studies Depression scale and the depression subscale of the Hospital Anxiety and… CONTINUE READING
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