Shared and unique genetic contributions to attention deficit/hyperactivity disorder and substance use disorders: A pilot study of six candidate genes

@article{Carpentier2013SharedAU,
  title={Shared and unique genetic contributions to attention deficit/hyperactivity disorder and substance use disorders: A pilot study of six candidate genes},
  author={Pieter Jan Carpentier and Alejandro Arias V{\'a}squez and Martine Hoogman and Marten H. Onnink and Cornelis C. Kan and J.J.S. Kooij and Remco R. R. Makkinje and Shelly Iskandar and Lambertus A Kiemeney and C.A.J. de Jong and Barbara Franke and Jan K. Buitelaar},
  journal={European Neuropsychopharmacology},
  year={2013},
  volume={23},
  pages={448-457}
}
The shared genetic basis of attention deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs) was explored by investigating the association of candidate risk factors in neurotransmitter genes with both disorders. One hundred seven methadone maintenance treatment patients, 36 having an ADHD diagnosis, 176 adult patients with ADHD without SUDs, and 500 healthy controls were genotyped for variants in the DRD4 (exon 3 VNTR), DRD5 (upstream VNTR), HTR1B (rs6296), DBH (rs2519152… CONTINUE READING
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