Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry.

@article{Palmer2015SharedAG,
  title={Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry.},
  author={Rohan H C Palmer and John E. McGeary and A Christopher Heath and Matthew C. Keller and Leslie Ann D Brick and Valerie S. Knopik},
  journal={Addiction},
  year={2015},
  volume={110 12},
  pages={1922-31}
}
BACKGROUND AND AIMS Genetic studies of alcohol dependence (AD) have identified several candidate loci and genes, but most observed effects are small and difficult to reproduce. A plausible explanation for inconsistent findings may be a violation of the assumption that genetic factors contributing to each of the seven DSM-IV criteria point to a single underlying dimension of risk. Given that recent twin studies suggest that the genetic architecture of AD is complex and probably involves multiple… CONTINUE READING