Shaping RNA structures with metal ions and metal ion complexes.

@article{Sigel2010ShapingRS,
  title={Shaping RNA structures with metal ions and metal ion complexes.},
  author={Roland K. O. Sigel and Sofia Gallo},
  journal={Chimia},
  year={2010},
  volume={64 3},
  pages={126-31}
}
The research in our laboratory focuses on the role of metal ions and their complexes in structure formation and folding of nucleic acids. Large catalytic RNAs, like group II introns and some riboswitches, as well as shorter RNAs and DNAs containing modified nucleotides for the assembly of nanodevices are examined. Abundant metal ions like Mg2+ or natural metabolites like coenzyme B12 are in the center of interest, but also other metal ions, complexes thereof and B12 derivatives are applied with… CONTINUE READING
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