Shape transformation and cytoskeletal reorganization in activated non-mammalian thrombocytes.

@article{Lee2004ShapeTA,
  title={Shape transformation and cytoskeletal reorganization in activated non-mammalian thrombocytes.},
  author={Keonbeom Lee and Todd F. Miller and Ivan Anastassov and William D. Cohen},
  journal={Cell biology international},
  year={2004},
  volume={28 4},
  pages={
          299-310
        }
}
The nucleated thrombocytes of non-mammalian vertebrates are partially flattened, ovoid cells morphologically distinct from mammalian platelets, and the extent of their functional equivalence is unknown. To test whether they resemble platelets in having similar F-actin-based post-activation stages, rapid fixation/extraction/labeling methods were developed to reveal cytoskeletal organization in dogfish thrombocytes by confocal microscopy. Unactivated cells contained cortical F-actin plus denser F… CONTINUE READING
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