Shape dynamics of a red blood cell in Poiseuille flow
@inproceedings{Agarwal2021ShapeDO, title={Shape dynamics of a red blood cell in Poiseuille flow}, author={Dhwanit Agarwal and George Biros}, year={2021} }
We use numerical simulations to study the dynamics of red blood cells (RBCs) in unconfined and confined Poiseuille flow. Previous numerical studies with 3D vesicles have indicated that the slipper shape observed in experiments at high capillary number can be attributed to the bistability due to the interplay of wall push and outward migration tendency at higher viscosity contrasts. In this paper, we study this outward migration and bistability using numerical simulations for 3D capsules and…
Figures and Tables from this paper
References
SHOWING 1-10 OF 40 REFERENCES
Red blood cell deformation in microconfined flow
- Engineering
- 2009
In this work, we report on a systematic fluidodynamic investigation of red blood cell (RBC) suspensions flowing in microcapillaries with diameters comparable to the cell size in vitro. By using…
Shape transitions of fluid vesicles and red blood cells in capillary flows.
- Physics, EngineeringProceedings of the National Academy of Sciences of the United States of America
- 2005
The dynamics of fluid vesicles and red blood cells in cylindrical capillary flow is studied by using a three-dimensional mesoscopic simulation approach, and slipper-like shapes of the RBC model are observed around the transition velocities.
Deformation and dynamics of red blood cells in flow through cylindrical microchannels.
- EngineeringSoft matter
- 2014
Mesoscale hydrodynamic simulations are employed to predict the phase diagram of shapes and dynamics of RBCs in cylindrical microchannels, which serve as idealized microvessels, for a wide range of channel confinements and flow rates.
Stable shapes of three-dimensional vesicles in unconfined and confined Poiseuille flow
- PhysicsPhysical Review Fluids
- 2020
We use numerical simulations to study the dynamics of three dimensional vesicles in unconfined and confined Poiseuille flow. Previous numerical studies have shown that when the fluid viscosity inside…
Flow-Induced Transitions of Red Blood Cell Shapes under Shear.
- EngineeringPhysical review letters
- 2018
Using two different simulation techniques, a state diagram is constructed of RBC shapes and dynamics in shear flow as a function of shear rate and viscosity contrast and it is shown that two different kinds of membrane buckling trigger the transition between subsequent RBC states.
On the problem of slipper shapes of red blood cells in the microvasculature.
- Materials ScienceMicrovascular research
- 2013
Dynamics of a large population of red blood cells under shear flow
- Engineering, PhysicsJournal of Fluid Mechanics
- 2019
An exhaustive description of the dynamics under shear flow of a large number of red blood cells in a dilute regime is proposed, which highlights and takes into account the dispersion in cell…
Complexity of vesicle microcirculation.
- BiologyPhysical review. E, Statistical, nonlinear, and soft matter physics
- 2011
A general scenario of how and why vesicles adopt their morphologies and dynamics among several distinct possibilities is provided and potentially points to nontrivial RBCs dynamics in the microvasculature.
Micro-macro link in rheology of erythrocyte and vesicle suspensions.
- BiologyBiophysical journal
- 2008
The viscosity of RBC suspensions reveals a previously unknown signature that may be used to detect blood flow disorders linked to pathologies that affect RBC shape and mechanical properties and opens future perspectives on setting up new diagnostic tools, with great efficiency even at very low hematocrit.
Full dynamics of a red blood cell in shear flow
- Engineering, BiologyProceedings of the National Academy of Sciences
- 2012
It is shown that contrary to common belief, when red blood cells flip into the flow, their orientation is determined by the shear rate, and the biconcave red cell shape is highly stable under moderate shear stresses, and is interpreted in terms of stress-free shape and elastic buckling.