Shape dependence of gold nanoparticles on in vivo acute toxicological effects and biodistribution.

@article{Sun2011ShapeDO,
  title={Shape dependence of gold nanoparticles on in vivo acute toxicological effects and biodistribution.},
  author={Ya-Nan Sun and Christina Wang and Xiu-Ming Zhang and Lei Ren and Xin-hua Tian},
  journal={Journal of nanoscience and nanotechnology},
  year={2011},
  volume={11 2},
  pages={
          1210-6
        }
}
The toxicity and biodistribution in vivo of various morphologies of Au nanoparticles (AuNPs) were studied by using KM mice. The quantitative analysis of Au in each tissue of mice was done by using the Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Sphere-shaped AuNPs displayed the best biocompatibility, compared with rod- and cube-shaped of AuNPs, and rod-shaped AuNPs was more toxic than cube-shaped AuNPs. In vivo biodistribution study revealed all AuNPs were preferentially accumulated… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS

First proof of bismuth oxide nanoparticles as efficient radiosensitisers on highly radioresistant cancer cells.

  • Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND