Shape-defining scaffolds for minimally invasive tissue engineering.

  title={Shape-defining scaffolds for minimally invasive tissue engineering.},
  author={Amanda J Thornton and Eben Alsberg and Megan A. Albertelli and David J Mooney},
  volume={77 12},
BACKGROUND Minimally invasive surgical procedures are increasingly important in medicine, but biomaterials consistent with this delivery approach that allow one to control the structure of the material after implantation are lacking. Biomaterials with shape-memorizing properties could permit minimally invasive delivery of cell transplantation constructs and enable the formation of new tissues or structures in vivo in desired shapes and sizes. METHODS Macroporous alginate hydrogel scaffolds… CONTINUE READING