Shank3 mutant mice display autistic-like behaviours and striatal dysfunction


Autism spectrum disorders (ASDs) comprise a range of disorders that share a core of neurobehavioural deficits characterized by widespread abnormalities in social interactions, deficits in communication as well as restricted interests and repetitive behaviours. The neurological basis and circuitry mechanisms underlying these abnormal behaviours are poorly… (More)
DOI: 10.1038/nature09965


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