Shallow Distance Dependence for Proton-Coupled Tyrosine Oxidation in Oligoproline Peptides.

@article{Koronkiewicz2020ShallowDD,
  title={Shallow Distance Dependence for Proton-Coupled Tyrosine Oxidation in Oligoproline Peptides.},
  author={Brian Koronkiewicz and John R. Swierk and Kevin P. Regan and James M. Mayer},
  journal={Journal of the American Chemical Society},
  year={2020}
}
We have explored the kinetic effect of increasing electron transfer distance in a biomimetic, proton coupled electron transfer system (PCET). Biological electron transfer is often simultaneous with proton transfer in order to avoid the high-energy, charged intermediates resulting from the stepwise transfer of protons and electrons. These concerted proton electron transfer (CPET) reactions are implicated in numerous biological electron transfer pathways. In many cases, proton transfer is coupled… 
4 Citations
Theoretical Study of Shallow Distance Dependence of Proton-Coupled Electron Transfer in Oligoproline Peptides.
TLDR
This theory predicted a less shallow distance dependence of the PCET rate constant when imidazole rather than hydrogen phosphate serves as the proton acceptor, even though their pKa values are similar, and was subsequently validated experimentally, illustrating that long-range electron transfer processes can be tuned by modifying the nature of the propton acceptor in concerted PCET processes.
Proton-Coupled Electron Transfer: The Engine of Energy Conversion and Storage.
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The proper design of PCET in these systems facilitates their implementation in the areas of centralized large scale grid storage of electricity and decentralized energy storage/conversion using only sunlight, air and any water source to produce fuel and food within a sustainable cycle for the biogenic elements of C, N and P.
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