Sexually dimorphic gene expression that overlaps maturation of type II pneumonocytes in fetal mouse lungs

@article{Simard2006SexuallyDG,
  title={Sexually dimorphic gene expression that overlaps maturation of type II pneumonocytes in fetal mouse lungs},
  author={Marc J Simard and Pierre R. Provost and Yves Tremblay},
  journal={Reproductive Biology and Endocrinology},
  year={2006},
  volume={4},
  pages={25 - 25}
}
BackgroundIn human, respiratory distress of the neonates, which occurs in prematurity, is prevalent in male. Late in gestation, maturation of type II pneumonocytes, and consequently the surge of surfactant synthesis are delayed in male fetuses compared with female fetuses. Although the presence of higher levels of androgens in male fetuses is thought to explain this sex difference, the identity of genes involved in lung maturation that are differentially modulated according to fetal sex is… CONTINUE READING

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