Sexually dimorphic gene expression in the heart of mice and men

@article{Isensee2007SexuallyDG,
  title={Sexually dimorphic gene expression in the heart of mice and men},
  author={Joerg Isensee and Henning Witt and Reinhard Pregla and Roland Hetzer and Vera Regitz-Zagrosek and Patricia Ruiz Noppinger},
  journal={Journal of Molecular Medicine (Berlin, Germany)},
  year={2007},
  volume={86},
  pages={61 - 74}
}
The prevalence and clinical manifestation of several cardiovascular diseases vary considerably with sex and age. Thus, a better understanding of the molecular basis of these differences may represent a starting point for an improved gender-specific medicine. Despite the fact that sex-specific differences have been observed in the cardiovascular system of humans and animal models, systematic analyses of sexual dimorphisms at the transcriptional level in the healthy heart are missing. Therefore… CONTINUE READING

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