Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation.

  title={Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation.},
  author={Phoebe Dewing and Tao Zhong Shi and Steve Horvath and Eric Vilain},
  journal={Brain research. Molecular brain research},
  volume={118 1-2},
The classic view of brain sexual differentiation and behavior is that gonadal steroid hormones act directly to promote sex differences in neural and behavioral development. In particular, the actions of testosterone and its metabolites induce a masculine pattern of brain development, while inhibiting feminine neural and behavioral patterns of differentiation. However, recent evidence indicates that gonadal hormones may not solely be responsible for sex differences in brain development and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
122 Citations
64 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 122 extracted citations


Publications referenced by this paper.
Showing 1-10 of 64 references

Boring , Sex differences in brain maturation during childhood and adolescence

  • E. F. Rissman, R. B. Simerly, +5 authors A. P. Arnold
  • Cereb . Cortex
  • 2001

Ferlin, Y chromosome microdeletions and alterations of spermatogenesis

  • C. Foresta, A. E. Moro
  • Endocr. Rev
  • 2001
1 Excerpt

Similar Papers

Loading similar papers…