Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice.

@article{Sorwell2008SexuallyDE,
  title={Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice.},
  author={Krystina G. Sorwell and Daniel W Wesson and Michael J Baum},
  journal={Behavioral neuroscience},
  year={2008},
  volume={122 4},
  pages={788-93}
}
We asked whether sex and adult estrogen exposure influence the detection thresholds for urinary odors used by mice to guide their social behaviors. Gonadectomized (GDX) male and female mice were trained on a two-choice food-motivated task to determine detection thresholds for male urinary odors. There was no significant sex difference in the detection of these odors by GDX subjects without hormone replacement. However, during treatment with estradiol benzoate (EB), GDX females, but not GDX… CONTINUE READING