Sexual transmission of HIV: infectiousness and prevention.

@article{Vernazza1999SexualTO,
  title={Sexual transmission of HIV: infectiousness and prevention.},
  author={Pietro Vernazza and J. J. Eron and Susan A. Fiscus and M. S. Cohen},
  journal={AIDS},
  year={1999},
  volume={13 2},
  pages={
          155-66
        }
}
HIV can be transmitted through contaminated blood and blood products; from a mother to her offspring during pregnancy childbirth or breast feeding; or through sexual contact. Sexual transmission remains by far the predominant mode of transmission. Vertical and blood borne transmission of HIV are highly predictable and very efficient modes. The recipient of a unit of contaminated blood nearly always becomes infected whereas only about 0.3% of people pierced with large bore needles seroconvert… 
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Biological Correlates of Sexual Transmission of HIV Practical Consequences and Potential Targets for Public Health
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An overview of sexually transmitted infections is given, and insight on their association with HIV infection, transmission risks and some control based interventions are given.
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  • Medicine, Biology
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 1998
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The current understanding of the mechanisms of sexual transmission and the biology of the transmitted HIV is reviewed, and a timely overview of candidate microbicides is presented, including past, ongoing and future clinical trials of HIV topical microbicide.
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TLDR
This review focuses on the genital and systemic factors that define the infectiousness of HIV and susceptibility to sexual transmission, including virological, microbiological and immunological parameters that affect HIV-1 pathogenesis and transmission.
Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
TLDR
There is an urgent need to develop innovative preventive measures that can reduce the transmission of these pathogens with minimal mucosa! irritation, and minimal effects on the vaginal flora and pH.
Occupational Blood Borne Infections: Prevention is Better than Cure
Use of assisted reproductive technology to prevent the transmission of HIV-1 in HIV-discordant couples desiring children☆
Genital Tract Infections and Perinatal Transmission of HIV
  • T. Taha, R. Gray
  • Medicine, Biology
    Annals of the New York Academy of Sciences
  • 2000
TLDR
It is conceivable that preventing ascending infection or reducing exposure of the infant to infectious material during birth could reduce MTCT, and antimicrobial therapy during pregnancy and intrapartum could reduce infectious causes of morbidity and mortality in infant and mother.
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