Sexual reproduction in the opportunistic human pathogen Aspergillus terreus.


Aspergillus terreus has a worldwide distribution in soil, constitutes the third most important cause of invasive aspergillosis in humans and is classically regarded as a strictly asexual species. Strains of A. terreus were characterized by ITS, β-tubulin and calmodulin sequences. Mating type was identified by amplifying and sequencing MAT1-1 and MAT1-2 genes. One MAT1-2 strain produced hyphal masses when crossed with four MAT1-1 strains on mixed cereal agar after 3 wk at 37 C. Cleistothecia formed inside the hyphal masses and produced asci containing smooth-walled ascospores with an equatorial protuberance. This is the first report of sexual reproduction in A. terreus.

DOI: 10.3852/11-426
Citations per Year

265 Citations

Semantic Scholar estimates that this publication has 265 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Arabatzis2013SexualRI, title={Sexual reproduction in the opportunistic human pathogen Aspergillus terreus.}, author={Michael Arabatzis and Aristea Velegraki}, journal={Mycologia}, year={2013}, volume={105 1}, pages={71-9} }