Sexual dysfunction in men taking systemic dermatologic medication: A systematic review.
@article{Zakhem2019SexualDI, title={Sexual dysfunction in men taking systemic dermatologic medication: A systematic review.}, author={George A. Zakhem and Julia E Goldberg and C C Motosko and Brandon E. Cohen and Roger S. Ho}, journal={Journal of the American Academy of Dermatology}, year={2019}, volume={81 1}, pages={ 163-172 } }
11 Citations
Sexual Health and Dysfunction in Patients With Rheumatoid Arthritis: A Cross-sectional Single-Center Study
- Medicine, PsychologySexual medicine
- 2020
Post-finasteride syndrome: a surmountable challenge for clinicians.
- Medicine, PsychologyFertility and sterility
- 2020
Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride.
- Psychology, MedicineJAMA dermatology
- 2020
In this pharmacovigilance case-noncase study, significant RORs of suicidality and psychological adverse events were associated withfinasteride use in patients younger than 45 years who used finasteride for alopecia.
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
- MedicineJournal of cosmetic dermatology
- 2021
Treating androgenetic alopecia therapy remains challenging as treatment selection involves ethical, evidence-based decision-making and consideration of each individual patient's needs, compliance, budget, extent of hair loss, and aesthetic goals, independent of potential financial benefits to the practitioners.
Androgenetic alopecia: effects of oral finasteride on hormone profile, reproduction and sexual function
- MedicineEndocrine
- 2020
Finasteride is associated with significant seminological and testosterone alterations, but no sexual dysfunctions were reported during treatment of these andrologically healthy subjects and it is advisable to perform a careful andrological evaluation before treatment.
Error in Author Surname.
- PsychologyJAMA dermatology
- 2021
This analysis identifies 2 avenues of investigation into the association of depression, anxiety, and suicidality with finasteride use in young patients with alopecia: mediation by adverse effects and confounding by stimulated reporting.
Treatment with Malva verticillata Seed Extracts Alleviates Alopecia via Activation of Wnt/β-catenin Signaling
- Biology
- 2020
Findings suggest that LA treatment induces hair growth by increasing DPC proliferation and alleviates androgenic alopecia by activating Wnt/β-catenin signaling in DPCs.
An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial.
- MedicineThe Journal of clinical and aesthetic dermatology
- 2020
The non-significant difference in clinical efficacy and safety to 3% minoxidil solution suggests that the herbal extract combination evaluated here could potentially be an alternative treatment with for AGA.
Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed
- BiologyMolecules
- 2021
The findings suggest that LA treatment may alleviate a testosterone-induced signaling molecule and induces HFDPCs growth by activating Wnt/β-catenin signaling and increasing several growth factors, such as vascular endothelial growth factor, insulin-like growth factor-1, hepatocyte growth factor and keratinocyte growthFactor, in a dose-dependent manner.
Association of Hair Loss With Suicidality and Psychological Adverse Events vs Finasteride Use-Reply.
- PsychologyJAMA dermatology
- 2021
References
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In most men who developed persistent sexual side effects despite the discontinuation of finasteride, the sexual dysfunction continued for many months or years, which should be made aware of the potential adverse medication effects.
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The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-finasteride use are characterized.
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Randomized Questionnaire Based Case–Control Research Study on Evaluation of Sexual Function in Indian Patients Taking Oral Finasteride for Androgenetic Alopecia
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Investigation of the sexual dysfunction in patients taking finasteride 1 mg for androgenetic alopecia showed no significant difference in sex-related problems with that of patients takingfinasteride and age matched controls, suggesting that sex- related issues are not a side effect of finasterid.
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The data indicates that use of 5ARI in men with sexual dysfunction does not significantly exacerbate pre-existing ejaculatory or erectile difficulties, but can further impair their sexual life by reducing sexual drive and spontaneous erection.
Finasteride 5 mg and sexual side effects: how many of these are related to a nocebo phenomenon?
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The burden of this nocebo effect (an adverse side effect that is not a direct result of the specific pharmacological action of the drug) has to be taken into account when managing finasteride sexual side effects.
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Reduced libido and erectile dysfunction: rarely reported side‐effects of methotrexate
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Two cases of male patients on methotrexate, both with recent onset symptoms of sexual dysfunction, are reported, to highlight these sideeffects to dermatologists currently using metotrexate.
Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review.
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Moderate-quality evidence suggests that daily use of oral finasteride increases hair count and improves patient and investigator assessment of hair appearance, while increasing the risk of sexual dysfunction.