Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension.

@article{Rands2012SexualDI,
  title={Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension.},
  author={Vicky F Rands and Dale M. Seth and Hiroyuki Kobori and Minolfa C. Prieto},
  journal={Gender medicine},
  year={2012},
  volume={9 4},
  pages={207-18}
}
BACKGROUND The intrarenal renin-angiotensin system contributes to hypertension by regulating sodium and water reabsorption throughout the nephron. Sex differences in the intrarenal components of the renin-angiotensin system have been involved in the greater incidence of high blood pressure and progression to kidney damage in males than females. OBJECTIVE This study investigated whether there is a sex difference in the intrarenal gene expression and urinary excretion of angiotensinogen (AGT… CONTINUE READING
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