Sexual differentiation of the central nervous system.

@article{Maclusky1981SexualDO,
  title={Sexual differentiation of the central nervous system.},
  author={Neil J Maclusky and Frederick Naftolin},
  journal={Science},
  year={1981},
  volume={211 4488},
  pages={1294-302}
}
Sexual differentiation of reproductive and behavior patterns is largely effected by hormones produced by the gonads. In many higher vertebrates, an integral part of this process is the induction of permanent and essentially irreversible sex differences in central nervous function, in response to gonadal hormones secreted early in development. 
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