Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin.

@article{Combs2003SexualDP,
  title={Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin.},
  author={Terry P. Combs and Anders H{\o}yer Berg and Michael W. Rajala and Simon Klebanov and Puneeth Iyengar and Jos{\'e} C Jimenez-Chillaron and Mary Elizabeth Patti and Sabra L Klein and Robert S. Weinstein and Phillip E Scherer},
  journal={Diabetes},
  year={2003},
  volume={52 2},
  pages={
          268-76
        }
}
Adiponectin or adipocyte complement-related protein of 30 kDa (Acrp30) is a circulating protein produced exclusively in adipocytes. Circulating Acrp30 levels have been associated with insulin sensitivity in adult mice and humans, yet the Acrp30 profile over the lifespan and its hormonal regulation in vivo have not been previously described. Hence, we set forth to determine whether hormonal and metabolic changes associated with sexual maturation, reproduction, aging, and calorie restriction… CONTINUE READING

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Gonadal HORMONAL REGULATION OF Acrp30 DIABETES

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