Sexual Reproduction and the Evolution of Microbial Pathogens

@article{Heitman2006SexualRA,
  title={Sexual Reproduction and the Evolution of Microbial Pathogens},
  author={J. Heitman},
  journal={Current Biology},
  year={2006},
  volume={16},
  pages={R711-R725}
}
  • J. Heitman
  • Published 2006
  • Medicine, Biology
  • Current Biology
Three common systemic human fungal pathogens--Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus--have retained all the machinery to engage in sexual reproduction, and yet their populations are often clonal with limited evidence for recombination. Striking parallels have emerged with four protozoan parasites that infect humans: Toxoplasma gondii, Trypanosoma brucei, Trypanosoma cruzi and Plasmodium falciparum. Limiting sexual reproduction appears to be a common virulence… Expand
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