Sexual Dimorphism of Cardiovascular Ischemia Susceptibility Is Mediated by Heme Oxygenase

@inproceedings{Psa2013SexualDO,
  title={Sexual Dimorphism of Cardiovascular Ischemia Susceptibility Is Mediated by Heme Oxygenase},
  author={Anik{\'o} P{\'o}sa and Krisztina Kupai and Rudolf M{\'e}nesi and Zita Szalai and Ren{\'a}ta Szab{\'o} and Zolt{\'a}n Pint{\'e}r and Gy{\"o}rgy P{\'a}lfi and Mariann Gy{\"o}ngy{\"o}si and Anik{\'o} Magyarin{\'e} Berk{\'o} and Imre J. Pavo and Csaba Varga},
  booktitle={Oxidative medicine and cellular longevity},
  year={2013}
}
We investigated the gender differences in heme-oxygenase (HO) enzyme, which produces endogenous vascular protective carbon monoxide (CO). We studied (1) the activity and expression of HO enzymes in the left ventricle (LV) and aorta, (2) basal increase in basal blood pressure provoked by arginine vasopressine (AVP) in vivo, (3) the heart perfusion induced by AVP, (4) the ST segment depression provoked by adrenaline and 30 seconds later phentolamine, and (5) the aorta ring contraction induced by… CONTINUE READING