Sexual Dimorphism in the Behavioral Responses and the Immunoendocrine Status in D-Galactose Induced Aging.

For almost twenty years, chronic systemic D-galactose, a monosaccharide abundantly present in milk products, fruits and vegetables, has been used as a tool to achieve models of accelerated aging. Its neurotoxicity, induced by abnormal accumulation of ROS and AGEs, has been widely reported. However, behavioral outcomes are still controversial and little is… CONTINUE READING