Sex steroids possess distinct stimulus properties in female and male mice.

@article{Peeters1992SexSP,
  title={Sex steroids possess distinct stimulus properties in female and male mice.},
  author={Bernard W. M. M. Peeters and Raphael Smets and Chris L. E. Broekkamp},
  journal={Brain research bulletin},
  year={1992},
  volume={28 2},
  pages={319-21}
}
Very few studies have investigated the aversive properties of sex steroids in animals. We studied these properties by testing oestradiol-3-benzoate, testosterone-propionate and progesterone in a conditioned taste aversion set-up, in intact female and male mice. Oestradiol-3-benzoate induced a taste aversion in both female and male mice; however, testosterone-propionate and progesterone had an effect only in females. These results show that sex steroids have intrinsic aversive properties. The… CONTINUE READING