Sex steroid modulation of neurohypophysial hormone receptors in human nonpregnant myometrium.

@article{Maggi1992SexSM,
  title={Sex steroid modulation of neurohypophysial hormone receptors in human nonpregnant myometrium.},
  author={Mario Maggi and Angela Magini and Antonio Fiscella and Stefano Giannini and Guido Fantoni and F G Toffoletti and Guido Massi and Mario Serio},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1992},
  volume={74 2},
  pages={385-92}
}
Neurohypophysial hormone receptors were studied in myometrial specimens obtained from nonpregnant women using binding and in vitro contractility studies. The mathematical modeling of self- and cross-competition curves among [3H]oxytocin (OT), [3H]arginine vasopressin, the V1 vasopressin (VP) antagonist [3H]d(CH2)5TyrMeAVP, the corresponding unlabeled peptides, and the OT agonist [Thr4, Gly7] OT strongly indicates the presence of multiple classes of OT and arginine vasopressin receptors. The… CONTINUE READING