Sex steroid hormones modulate the activation of murine peritoneal macrophages: receptor mediated modulation.

@article{Savita1998SexSH,
  title={Sex steroid hormones modulate the activation of murine peritoneal macrophages: receptor mediated modulation.},
  author={Savita and Umesh Rai},
  journal={Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology},
  year={1998},
  volume={119 2},
  pages={199-204}
}
  • Savita, Umesh Rai
  • Published 1998 in
    Comparative biochemistry and physiology. Part C…
The comparative dose and time-dependent effects of male and female sex steroid hormones on nitrite release by murine peritoneal macrophages (M phi) stimulated by LPS were studied. M phi from gonadectomized mice released larger amounts of nitrite on LPS stimulation than controls; although nitrite release was significantly greater in castrated males than in ovariectomized females, suggesting that sex hormone deprivation results in an increase in nitrite release. This was further confirmed by in… CONTINUE READING

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