Sex-specific splicing of the honeybee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway.

@article{Cho2007SexspecificSO,
  title={Sex-specific splicing of the honeybee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway.},
  author={Soochin Cho and Zachary Y Huang and Jianzhi Zhang},
  journal={Genetics},
  year={2007},
  volume={177 3},
  pages={1733-41}
}
Sex-determination mechanisms vary greatly among taxa. It has been proposed that genetic sex-determination pathways evolve in reverse order from the final step in the pathway to the first step. Consistent with this hypothesis, doublesex (dsx), the most downstream gene in the Drosophila sex-determination cascade that determines most sexual phenotypes also determines sex in other dipterans and the silk moth, while the upstream genes vary among these species. However, it is unknown when dsx was… CONTINUE READING
49 Citations
21 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 21 references

Analysis of the biological functions of a doublesex homologue in Bombyx mori

  • S. F unaguma, T. K anda, T. T amura, T. S himada
  • Dev . Genes Evol .
  • 2005

The mechanism of sex - specific splicing at the doublesex gene is different between Drosophila melanogaster and Bombyx mori

  • S. F unaguma, T. K anda, T. T amura, T. S himada
  • sect Biochem . Mol . Biol .
  • 2003

Similar Papers

Loading similar papers…