Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage.

@article{Sosnowski1989SexspecificAS,
  title={Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage.},
  author={Barbara A Sosnowski and John M. Belote and Michael Aidan McKeown},
  journal={Cell},
  year={1989},
  volume={58 3},
  pages={449-59}
}
Sex-specific alternative splicing of RNA from the Drosophila transformer gene involves competition between two 3' splice sites. In the absence of Sex-lethal activity (as in males), only one site functions; in the presence of Sex-lethal activity (as in females), both sites function. Information for sex-specific splice site choice is contained within the intron itself. Deletions of the splice site used in males lead to Sex-lethal-independent use of the otherwise female-specific site. The relative… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 75 extracted citations

Similar Papers

Loading similar papers…