Sex-related changes in estrogen receptors and aromatase gene expression and enzymatic activity during early development and sex differentiation in the European sea bass (Dicentrarchus labrax).

@article{Blzquez2008SexrelatedCI,
  title={Sex-related changes in estrogen receptors and aromatase gene expression and enzymatic activity during early development and sex differentiation in the European sea bass (Dicentrarchus labrax).},
  author={Mercedes Bl{\'a}zquez and Alicia A. Gonzalez and Maria Papadaki and Constantinos C. Mylonas and Francesc Piferrer},
  journal={General and comparative endocrinology},
  year={2008},
  volume={158 1},
  pages={95-101}
}
The present study addresses the role of aromatase and estrogen receptors in sex differentiation and development. With this purpose, a sea bass female- and a male-dominant group were obtained by successive size gradings since in this species females are already larger than males at the time of sex differentiation. Changes in cyp19a and cyp19b gene expression and enzymatic activity were monitored by a validated real-time PCR and a tritiated water assay, respectively, during early development and… CONTINUE READING

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